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How does the sars-cov-2 vaccine work?

Many of us are now faced with the decision of whether or not to accept the vaccine on offer. To facilitate the decision somewhat, I will explain here what I have learned about the way these vaccines work.

T-cell memory is most crucial in the protection against viral infections, although antibodies also play an important role. When defining immunity as virus-binding antibodies in the blood, it can be argued that the virus immunity is short-lived. This is also fundamentally wrong. The antibody levels directed against the virus circulating in the blood decrease after the infection has disappeared, as they are no longer needed, but T-cell immunity remains and can be activated quickly. The antibodies work less well against viruses that are so altered (mutated) that they are not considered the same virus.

Why do you want to mislead the public in this subtle way you may wonder? The reason may be that you want to be able to compare natural immunity with vaccine immunity. Many vaccines mainly activate only antibody responses and are mainly focused on the variable surface proteins in this case the nail protein. When the virus has changed sufficiently, the vaccine protection no longer works and you then have to get vaccinated with a new vaccine to get new specific antibodies. The annual flu vaccinations of the elderly and other risk groups are examples of this. However, the immunological memory after a flu infection lasts much longer precisely due to the much broader T-cell immunity, which means that most people only get the flu for a few times in their lives. Therefore, mass vaccination with coronavina vaccine may prevent the establishment of T cell immunity to the entire virus in the population. Against this background, therefore, mass vaccination does not seem to be a wise strategy other than for the vaccine industry. For the elderly in the risk group, vaccine protection can be crucial in the short term, but for younger healthy individuals it is disadvantageous and for the entire population very risky in the long run. When the virus has mutated sufficiently, the population is left without protection. Could that be the intention? You then have to launch new vaccination campaigns that are extremely lucrative for Big Pharma.

Messenger vaccine – mRNA

In 2020, the vaccine industry has developed a variety of vaccines to be used to create some kind of immunity to the SARS-CoV-2 virus. The development has been accelerated in a very short time, which of course increases the risks of unpleasant setbacks in the form of unexpected side effects. The normal development time for testing a new vaccine is approx. 10 years.

The ones that stand out are Pfizer / BioNTech’s and Moderna’s vaccines, which are genetically modified messenger or mRNA vaccines. They are not vaccines in the traditional sense, but a preparation that contains genetic material called RNA that is taken up by the cells and programs them to form copies of the virus cell’s nail proteins or S-proteins. The nail proteins are the small “crowns” that protrude from the virus particle and that gave the virus type its name – coronavirus.

The nail proteins or crowns on the virus particles work so that when infected they connect to receptors on the host individual’s cells and allow the virus to enter the cell and cause it to start reproducing virus particles and the person becomes infected. If the immune system can in any way be made to neutralize the nail protein of the virus particles, the virus cannot enter the cells and multiply.

The task of the vaccines is to start the immune system by first getting the cells to produce nail proteins. The central component of these mRNA vaccines is a molecule called messenger RNA or mRNA. The molecule carries genetic material that our cells can use to describe how to produce the nail proteins of the coronavirus. When mRNA enters the cell, it begins to produce copies of the protein, which then exit the host cell and enter the bloodstream.

The expected immunity is created by the body’s normal immune system reacting to the nail proteins produced in this way and producing antibodies against it. When the latter person is infected with the whole virus, the antibodies recognize the nail protein and therefore attack the nail of the virus. For this to work, the person’s immune system must function satisfactorily, which is not always the case.

There have been some reports that Pfizer’s and Moderna’s vaccines need to be kept properly refrigerated, which greatly complicates handling. Pfizers in minus 70 degrees C and Modernas in minus 20. This is because the mRNA molecule is very fragile. This also means that it cannot be injected directly, but must be wrapped in a protective grease casing.

To make it easier for mRNA to enter the cells undamaged, this has been enclosed in nanoparticles with a cover of lipids. It is a fat-like substance that makes it fat-soluble, making absorption much better. This system is widely used in the pharmaceutical industry and complements production to formulate high quality solid lipid nanoparticles and liposomes loaded with pharmaceuticals, vitamins, antioxidants, peptides and other bioactive compounds. Ultrasonic nano-emulsification and encapsulation is a reliable technology to produce large quantities of high quality nano carriers such as solid lipid nanoparticles, nano-structured lipid carriers and liposomes.

Polyethylene glycol (PEG) is a toxic ingredient found in mRNA vaccines. This synthetic polymer is used to coat the lipid nanoparticles so that they can bypass the detection of the body’s immune system. Nonprofit Children’s Health Defense published an article in August 2020 with a warning about the dangers of PEG. It describes the negative side effects people may experience when immunized with a PEG-containing vaccine, such as tumor growth and life-threatening hypersensitivity.

The differences between Pfizer’s and Moderna’s vaccines are minimal and include about the exact components of the protective cover. The vaccines are thus injected into the mRNA molecules wrapped in lipid nanoparticles in the body. Via the absorbed lipid droplet, the mRNA enters the cells. There, ribosomes are taken care of, which reads from the mRNA’s instructions on how the cell should produce the nail protein.

The immune system has three types of defense mechanisms. There are various white blood cell antigen presenting cells, B cells, killer T cells and T helper cells. Antigen-presenting cells can take up nail proteins and their fragments found in the remains of a dead cell. Even in these cells, parts of the protein can come to the surface. There, they are discovered by the immune system’s T-helper cells, which cause the immune system to start its work.

The T helper cells can activate the B cells. These then begin to give off antibodies whose job it is to block the spikes of the nail protein. The antibodies can thus get caught in the protruding nail protein tags of the virus, which means that the virus cannot enter and infect other cells. The killer T cells are activated by the antigen presenting cells. Their job is to find and destroy cells that have the coronavirus’ protein tags on the outside.

Pfizer / Biontech’s vaccine is said to have an efficiency of 95 percent Modernas has an efficiency of 94.1 percent. Both vaccines were quickly approved for use in the United States and the European Union. However, it is not yet clear exactly how long the body’s immune system will remember after a vaccination, ie it is not known how long the vaccines are effective. However, experience from the seasonal flu vaccine suggests that it may at most be a year. On the other hand, those who have been ill and recovered have a much longer and more robust natural immune system against similar infections that are likely to last much longer, perhaps a lifetime.

Vector vaccine

Russian Sputnik V, Astra Zeneca’s vaccine (sometimes called the Oxford vaccine) and Janssen’s vaccine (sometimes referred to as Johnson & Johnson’s vaccine) are viral vector vaccines. Sputnik V has according to Lancet reported an efficiency of 91.6 percent, Astra Zeneca an efficiency of 62 or 90 percent, depending on the dosage. Sputnik V, the longest-used vaccine, has reported relatively few side effects.

The virus vector vaccines may at first glance resemble the mRNA vaccines because both involve producing nail proteins and causing the body to establish an immune system against them. However, the vector vaccines introduce into the cells the description of how to produce the nail protein in a completely different and proven way. This is done via a double-stranded DNA, instead of mRNA, and the instructions are packaged in another virus and not in lipid nanoparticles with additives of the toxic PEG.

The virus used to transport the job description is a so-called adenovirus, which is the culprit behind many of our common infections, but which in this case has been modified to carry the DNA instruction. The advantage of this technique is that DNA is not as fragile as mRNA, and the adenovirus is a stable protection. Therefore, these vaccines do not need to be stored in severe cold like Pfizers and Modernas and thus become much easier and cheaper to handle. It is also cheaper to buy.

When a viral vector vaccine is injected, the adenovirus carrying the DNA with the description for the production of the nail protein enters the cells. They devour the virus and once inside, the adenovirus enters the cell nucleus. There, the adenovirus releases its DNA. The deactivated adenovirus cannot copy itself, but the job description for the coronavirus’ nail proteins can be read by the cells and copied to RNA, which in turn causes the cells to start producing the nail proteins. This initiates the same procedure as for the mRNA vaccines, to create immunity against the nail proteins and thus also against the coronavirus, which of course has nail proteins on the surface. But as I said, for it to work, the immune system must be somewhat intact. If the nail proteins are not eliminated by the immune system, they in turn can cause severe vascular problems.

There is today both good prophylaxis and cure for covid-19. Those who have a good vitamin D status are 15 times less likely to die from the disease compared to those who have vitamin D deficiency, which is the vast majority. In most cases, covid-19 can be cured relatively easily if hydroxychloroquine is added or ivermectin during the first days of illness.

It is, of course, completely reprehensible to try to force people to be vaccinated against their will, as politicians are now doing. An unvaccinated person should not pose a threat of infection to anyone other than those who have also chosen not to be vaccinated. My advice is to familiarize yourself with how these vaccines work and weigh your own risk of infection against the risk of side effects of the vaccine. I myself will wait until I know enough about the risks of being able to make a well-founded choice. If you have had a covid-19 infection, you have a far better protection than what a vaccine can offer, then an additional vaccination only means an increased risk and no benefit.

You have a constitutionally protected right to decide over your own body, so do not be forced to make a decision by the intense propaganda that politicians and the media are now trumpeting. This is about revenues of hundreds of billions for the pharmaceutical industry complex and then you can not trust anyone more than yourself.

Lars Bern

Original text: anthropocene.live, How does the sars-cov-2 vaccine work?

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